Phone Envelope
Search

We help you to accelerate drug discovery

Your partner in assay development, lab automation,
ultra-High Throughput Screening and hit-to-lead biological profiling

Are you looking for lead candidate compounds for your target and do you want your drug discovery program to be more efficient, in terms of both time and cost?

Pivot Park Screening Centre is your optimal partner in early drug discovery

Projects are tailored to your requirements; We provide drug discovery services in the fields of biochemical, biophysical and cellular assay development, lab automation, ultra-High Throughput Screening (uHTS, usually in 1536-well format) and hit-to-lead biological profiling, in order to find novel leads for drug development. 

Furthermore all major read-out modalities are available in-house ensuring rapid generation of high-quality hits. As first CRO we integrated Mass Spectrometry (MALDI-TOF MS) into our uHTS system, thus providing you with the opportunity to run label-based and also label-free assays.

You can either bring your own small molecule library or use our 300K IP-free druglike compound library. Our fully automated robot system can handle at least 2 mln. compounds per screen. As a matter of fact, over the past 10 years we have successfully completed more than 150 screening campaigns.

We are continuously expanding our early drug discovery know-how, compound library and services to add value to our vibrant client network and the pharmaceutical R&D community.

In order to help you accelerate drug discovery for a healthier society. 

How can we help you?

What makes Pivot Park Screening Centre unique?

  • Integrated approach for early drug discovery
  • Rapid generation of high-quality hits; All major read-out modalities available in-house including MALDI-TOF MS
  • Handling of large customer compound libraries; bring your own small molecule library or use our 300k in-house compound library
  • Big pharma-like uHTS set-up coupled with top-notch read-out technologies
  • Very experienced screening site for pharma-clients, charities and start-ups
  • Broad knowledge in different assay development-solutions
  • From disease targets to high-quality starting points for drug development
  • Affinity Selection Mass Spectrometry (ASMS)

Interested? Get in touch and we’ll help you accelerate your drug discovery.

Download our brochure

Pivot Park Sreening Centre is located at Pivot Park in the Netherlands, because it focuses on pharmaceutical R&D. It is a particularly inspiring campus for open innovation in life sciences.

Early drug discovery

Discover what we can do for you

Assay Development solutions from Pivot Park Screening Centre

Discover our services

We offer amongst others assay development, hit identification, triaging as well as hit-to-lead profiling services to help you succeed in the early stages of the drug discovery process.

 

ultra-High Throughput screening system at Pivot Park Screening Centre

Discover our infrastructure

Pivot Park Screening Centre not only is equipped with advanced robotic systems but also ultra High Throughput Screening (uHTS), Mass Spectrometry and other lab automation services to accelerate your drug discovery.

The PPSC network - background picture

Discover our projects

We work together with our customers and partners on the bases of open communication and trust. 

 

 

 

 

Animation for the European Lead Factory

Discover Funding options

Funds available to promote the discovery of new medicines via assay development or ultra-High Throughput screening. 




Some facts & figures about Pivot Park Screening Centre

0 mil.
Compounds screened
0 mil.
Data points in 2022
0
Screens per year
0
Assays per year
0
Hit-to-lead programs finalized

Blog, News, Events & Stories

Data management
PPSC

The Crucial Role of Efficient Data Management in Accelerating Drug Discovery

Discover the key role of effective data handling in pharmaceutical research with Pivot Park Screening Centre. Our state-of-the-art automation and screening infrastructure, coupled with ISO certifications and diverse data analysis techniques, ensure secure and quality data. Learn how our multidisciplinary team accelerates drug discovery, making us your trusted partner in early drug discovery efforts.

Read More »
28 November 2023
Five reasons for a startup to outsource a screen at PPSC

Are you a startup?

Read all about the 5 reasons to outsource a screen at PPSC

Download PDF
Is you assay amendable to uHTS? Seven aspects to consider

7 aspects to assess

Is your assay amendable to ultra-High-Throughput Screening?
Seven aspects to consider…

Download PDF

What our clients say

"Pivot Park Screening Centre is an ideal partner for Bayer AG with demonstrated industry-standard capabilities, knowledge in developing novel HTS assays and excellence in managing early discovery projects with exemplary efficiency and flexibility."
Bayer
Bayer
“Thanks again Pivot Park Screening Centre for the nice work and great data. You guys have made spectacular progress. You made my day!”
ELF PO
ELF PO
"We had the opportunity to develop an assay on the new rapifleX™ MALDI TOF system. Our success was basically a direct result of clear communication and scientific rigour provided by the Pivot Park Screening Centre team."
Biopharmaceutical company from the East Coast
It was great working with such professional and technically excellent set of screening scientists and management. I would thoroughly recommend anyone considering outsourcing assay development and high-throughput screening to consider working with Pivot Park Screening Centre.
James Westcott, PhD Director of M:M Bio
We had a very efficient and high quality uHTS collaboration with Pivot Park Screening Centre.
Ambagon
We really appreciate working with Pivot Park Screening Centre (PPSC). The staff is knowledgeable and always open for discussions, ad-hoc meetings and suggestions and has short lead times. It is always a delight to read the reports of PPSC: very structured, contains the proper amount of information and high quality.
Xenikos
"Odyssey Therapeutics has recently run a complex, cell-based HTS at Pivot Park Screening Centre. I was particularly impressed by their “can-do” spirit in the rapid miniaturization and execution of the project, thereby cutting reagent costs and timelines. The culture of a company like PPSC, which includes a refreshing directness and transparency, is a good fit with the no-nonsense attitude of a demanding biotech partner. On the technical front, PPSC boasts robust automation resulting in excellent screening results and plate statistics. Together with the assay optimization and adaptation, the ultimate robotic execution of the screen ran nearly flawlessly. Having personally managed a large, well-equipped HTS facility for many years, the collaboration with PPSC was like going back home!"
Jeff HermesExecutive VP and Head of Enabling Sciences at Odyssey Therapeutics
We had the chance to collaborate on a fruitful program with PPSC that led to a high impact outcome for MT-act. Great and very professional team!
MT-Act
PPSC has screened 3 challenging targets for us, and for 2 of these tractable hits were delivered. Overall we are very satisfied with the services provided by PPSC and would recommend them for collaboration.
Karolinska Institute
Our primary assay has suffered from interfering fluorescent compounds. By transitioning to a label-free enzyme assay on the MALDI-TOF platform at PPSC, we were able to develop assays using a variety of physiological substrates of the target and evaluate compound potency without worrying about interference of the detection technology. I will definitely consider developing a label-free enzyme assay as the primary assay for hit finding in the future and would happily engage PPSC for this project!
Grey Wolf TherapeuticsHead of Biology
Previous
Next

Customers & Partners

Universiteit Leiden Logo
Ambagon logo
Radboud UMC logo
Bayer logo
Xenikos Logo
Radboud University Nijmegen logo
Galapagos logo
UCB logo
Merck logo
NTRC logo
Medicines for Malaria Ventures logo
MM Bio_Molecule 2 Medicine
Ncardia logo
Antoni van Leeuwenhoek logo
Bio Axis Research Logo
Aduro Biotech Logo
European Lead Factory Logo
Logo Odyssey Therapeutics
Tenwise Logo
Vivenics logo
Projects

Can we help you to accelerate
your drug discovery?

Request a quotation
Contact our scientist
Pivot Park Screening Centre logo white
DNV logo for ISO9001 and ISO27001 certification

Contact

+31 (0) 412 846050 info@ppscreeningcentre.com
Linkedin-in Youtube

Subscribe to our newsletter

Location

Pivot Park – Banting Building (RE600)
Kloosterstraat 9
5349 AB Oss
The Netherlands

Shipping address

Pivot Park Screening Centre
Building OP
Kloosterstraat 9 
5349 AB Oss
The Netherlands

Disclaimer  |  Privacy Policy

Thank you for you interest!

To download this publication we would like to receive your e-mail. 

Thank you for you interest!

To download this publication we would like to receive your e-mail. 

Thank you for you interest!

To download this publication we would like to receive your e-mail. 

Join us on Linkedin