Watch this webinar to learn about diversity in compound libraries:
- Lipinski rules, pains’ concerns and drug-likeness
- Commercially available libraries
- Judging the quality of a library
- Storage and usage of libraries
In this webinar we will guide you through the process of building your own high-quality library and demonstrate how to analyze content of diverse compound libraries for HTS.
High Throughput Screening (HTS) requires the availability of large compound libraries, typically hundreds of thousands or even millions of compounds. Dr. Steven van Helden of Pivot Park Screening Centre (PPSC) will introduce you to the basic concepts of building a diverse compound library. Steven will demonstrate how to build a drug like library that maximizes your probability of finding useful hits. Finally, he will share insights on how to maintain the quality of your library over the years to come.
About the presenter:
Dr. Steven van Helden, Chief Technology Officer at Pivot Park Screening Centre, studied chemistry at Utrecht University and, after obtaining his Ph.D. , worked in various roles in pharmaceutical industry for 20 years. Since 2003 he has been responsible for High Throughput Screening (HTS) operations and strategy at Organon/MSD. After the closure of those research facilities he developed a business plan for continuation of the screening activities in Oss, The Netherlands. This led to the formation of the Pivot Park Screening Centre (PPSC) in 2012, and a central role of this company in the European Lead Factory.
