Identification and Development of Biphenyl Substituted Iminosugars as Improved Dual Glucosylceramide Synthase/Neutral Glucosylceramidase Inhibitors

Med. Chem. 2014, 57, 21, 9096–9104 Publication Date:September 24, 2014

Recent publications

Hit Discovery for Public Target Programs in the European Lead Factory: Experiences and Output from Assay Development and Ultra-High-Throughput Screening

High-Throughput Fluorescence-Based Activity Assay for Arginase-1

Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice

Synthesis and Structure‐Activity Relationships of N‐(4‐Benzamidino)‐Oxazolidinones: Potent and Selective Inhibitors of Kallikrein‐Related Peptidase 6

High throughput screening in calcium transient assay to assess cardiotoxicity of compounds using hiPSC-derived cardiomyocytes

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