Mass Spectrometry (MS) is now integrated as read-out technology into our uHTS system. This technology can directly track the molecule(s) of interest without the hassle of introducing labels and the risk of these labels interfering with other components in your assay. Label-free assays can reduce the number of false positives and false negatives in your screen, which will make the hit-to-lead phase of your drug discovery programme more time- and cost-effective.

By combining the RapifleX™ MALDI PharmaPulse® from Bruker with the CyBio® Well Vario pipettor from Analytik Jena for automated sample spotting, we can handle 1536-well plates fully automated and screen MS-based assays up to a speed of 0.5 seconds per sample. Additionally, this system has the option for on-target washing of your samples for reduced signal-quenching and increased assay quality and robustness.