One of our customers approached Pivot Park Screening Centre with an exciting drug discovery opportunity. They shared their biological target without an established assay. They needed our support to bring their project from target identification to a functioning screening assay.
At Pivot Park Screening Centre, we are specialized in assay development, and our team works closely with the customer to understand their target’s unique biology and the requirements of their drug discovery project. Leveraging our expertise in both biochemical and cellular assays, we design and optimize a robust assay tailored to our customer’s target.
Once the initial assay was developed, our next step was to miniaturize and transform it for high-throughput screening (HTS) format. We scaled the assay to 1536-well format, ensuring it would deliver reliable and reproducible results at the scale needed for large screening campaigns while saving on compound and reagents and thus costs.
Our added value in designing your High Throughput Screening assay lies in our team’s expertise in selecting the optimal readout technology, as well as optimizing and miniaturizing the process for a fully automated 1536-well screen
Our customer was impressed by the flexibility and expertise we offered throughout the assay development process. Whether it was selecting the most appropriate readout technology (fluorescence, luminescence, or mass spectrometry), optimizing assay conditions, or ensuring the assay’s robustness, we provided a solution that met their unique project needs.
With the assay successfully developed and validated, our customer was now ready to move forward with high-throughput screening, confident in the quality and performance of the assay. This complete support from target to assay allowed our customer to rapidly progress to the next stage of their drug discovery project.
This case shows how Pivot Park Screening Centre can assist you even at the earliest stages of drug discovery. We provide the expertise and technology to accelerate your discovery process and ensure high-quality results.
If you’re looking to accelerate your drug discovery program but need help with your assay development, Pivot Park Screening Centre is there to help.
Contact Pivot Park Screening Centre today to discuss how we can support your next project.
Pivot Park – Banting Building (RE600)
Kloosterstraat 9
5349 AB Oss
The Netherlands
Pivot Park Screening Centre
Building OP
Kloosterstraat 9
5349 AB Oss
The Netherlands