High quality compound library

for your drug discovery screens

Pivot Park Screening Centre has a library of 300,000 high-quality drug-like compounds available to perform your drug discovery screens. As well, we have access to the unique ELF compound library of >0.5 million compounds.

 

The library consists of four sub-libraries, which have been combined to form a highly diverse collection.
Included in the library are subsets of known drugs (approximately 1200) and known assay interfering compounds (approximately 400) that can be used for drug-repurposing studies and assay validation.

The collection consists of four sub-libraries
each of different provenance:

PPSC Compound Library in Numbers

130K Historical collection.
A set of compounds inherited from Organon/MSD when PPSC was established. This set contains screening molecules which were carefully selected using cheminformatics tools.

 

87K acquired in 2012.
This set was selected by PPSC, from commercial vendors, to increase the diversity of the historical collection. The latest insights in desired molecular properties were applied. About 70% of this set was examined by experienced medicinal chemists to ensure tractable compounds were included in this set.

 

8K pharma origin.
Compounds synthesised at Organon/MSD

 

70K BioAscent extension.
This is a subset of the collection of the Scottish company BioAscent. It adds further diversity to the above sets.

Shared libraries,
a cost-effective solution

PPSC has extensive knowledge of screening customers’ libraries. As a result of its experience in the European Lead Factory, it is a front-runner in screening shared libraries. PPSC offers a new solution for screening compound libraries that are shared among partners, and provides cost-effective access to a larger chemical space.