High quality Structure-Activity Relationship data

with our biological profiling services.

PPSC’s hit-to-lead biological profiling services support knowledge-based lead discovery programmes with existing small-molecule starting points or hit expansion post uHTS campaigns. ​We regularly generate high-quality Structure-Activity Relationship (SAR) biological data in existing or tailored in vitro assay panels to guide chemical synthesis.​ ​In collaboration with our chemistry partners, we can provide a full hit-to-lead package including early in vitro ADME-Tox profiling to identify high-quality preclinical candidates

Hit-to-lead biological profiling