Ultra-High Throughput Hit Discovery against Protein-Protein interactions: A SAR CoV-2 Showcase

Why small-molecule inhibitors of COVID-19?

Large health and economic damage
Limited effect of repurposed antiviral drugs
Vaccination stretches beyond 2023
Vaccines are strain & mutation-sensitive

Small-molecule inhibitors offer:

Broad activity
Controllable (half-life/biodistribution)
Less immunogenicity
Patient friendly administration routes
Standalone and/or combination treatment options

Recent publications

Publications in collaboration with Pivot Park Screening Centre

Publications – In collaboration with Pivot Park Screening Centre

Replenishing the malaria drug discovery pipeline

Replenishing the malaria drug discovery pipeline: Screening and hit evaluation of the MMV Hit Generation Library 1 (HGL1) against asexual blood stage Plasmodium falciparum, using a nano luciferase reporter read-out

Pivot Park Screening Centre is equipped with advanced robotic systems and offers ultra-High-Throughput Screening

The Discovery of New Inhibitors of Insulin-Regulated Aminopeptidase by a High-Throughput Screening of 400,000 Drug-like Compounds

ultra-high throughput-based screening

The European Lead Factory: Results from a decade of collaborative, public–private, drug discovery programs

FLIPR whitepaper: High-Throughput Hit Discovery for Ion Channels and G Protein-Coupled Receptors

High-Throughput Hit Discovery for Ion Channels and G Protein-Coupled Receptors

Customers & Partners

Can we help you to accelerate
your drug discovery?

Contact

+31 (0) 412 846050 info@ppscreeningcentre.com

subscribe to our newsletter

Location

Pivot Park – Banting Building (RE600)
Kloosterstraat 9
5349 AB Oss
The Netherlands

Shipping address

Pivot Park Screening Centre
Building OP
Kloosterstraat 9
5349 AB Oss
The Netherlands

Disclaimer | Privacy Policy