Webinar-on-demand: Hit discovery for trained immunity and tolerance

Webinar_hit discovery for trained immunity and tolerance

Hit discovery for trained immunity and tolerance against epigenetic targets

Watch this webinar to learn about: 

  • Trained immunity.
  • The role of epigenetic targets in trained immunity.
  • Hit discovery through ultra-High throughput screening of large libraries.
  • Industry standard H2L biological profiling frameworks.

In this webinar we will focus on epigenetic targets:

  • Center for Open Innovation in Lead Discovery (COILED) is a collaborative drug discovery program focused on epigenetic targets.
  • Modulation of trained innate immunity for treatment of hyper-inflammation and immune deficiency-driven diseases like sepsis and cancer.
  • ultra-High Throughput Screening (uHTS) campaign of 300,000 diverse set of compounds has led to the identification of 3 novel scaffolds (starting points) that progressed into Hit-to-Lead (H2L) phase.

About the presenter: 

Dr. Saman Honarnejad – Chief Scientific Officer is a biotechnologist with over a decade of experience in High Throughput Biology. At Pivot Park Screening Centre (PPSC) in Oss, the Netherlands, he is involved in cellular and biochemical assay development, ultra-High Throughput screening (uHTS) and Hit-to-Lead (H2L) biological compound profiling within a wide range of commercial, academic and public-private partnership projects including the European Lead Factory (ELF).

Prior to joining PPSC in 2017, he was active in high-content compound profiling method development at Max-Planck Institute (Germany), Harvard Medical School (United States) and Heidelberg University (Germany) and further optimized microarray-based cDNA/RNAi functional screening assays at the European Molecular Biology Laboratory (EMBL).

(This webinar will be during 30 minutes)

Thank you for you interest!

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